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Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy

✍ Scribed by Alastair M. Thompson; Andrea Johnson; Philip Quinlan; Grantland Hillman; Marcel Fontecha; Susan E. Bray; Colin A. Purdie; Lee B. Jordan; Roberta Ferraldeschi; Ayshe Latif; Kirsten D. Hadfield; Robert B. Clarke; Linda Ashcroft; D. Gareth Evans; Anthony Howell; Michele Nikoloff; Jeffrey Lawrence; William G. Newman


Publisher
Springer US
Year
2010
Tongue
English
Weight
321 KB
Volume
125
Category
Article
ISSN
0167-6806

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Genetic polymorphisms of CYP2D6*10 and C
✍ Matthew Goetz; Vera Suman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 56 KB πŸ‘ 1 views

The study by Okishiro et al 1 concludes that the cytochrome P450 (CYP) genotype CYP2D6\*10/\*10 is unlikely to have a clinically significant impact on prognosis in women with breast cancer who receive adjuvant tamoxifen. However, several aspects of the study by Okishiro et al call their conclusions