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Lack of any association between functionally significantCYP2D6polymorphisms and clinical outcomes in early breast cancer patients receiving adjuvant tamoxifen treatment

โœ Scribed by In Hae Park; Jungsil Ro; Sohee Park; Hyeong-Seok Lim; Keun Seok Lee; Han Sung Kang; So-Youn Jung; Seeyeon Lee


Publisher
Springer US
Year
2011
Tongue
English
Weight
333 KB
Volume
131
Category
Article
ISSN
0167-6806

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Genetic polymorphisms of CYP2D6*10 and C
โœ Matthew Goetz; Vera Suman ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 56 KB ๐Ÿ‘ 1 views

The study by Okishiro et al 1 concludes that the cytochrome P450 (CYP) genotype CYP2D6\*10/\*10 is unlikely to have a clinically significant impact on prognosis in women with breast cancer who receive adjuvant tamoxifen. However, several aspects of the study by Okishiro et al call their conclusions