## Abstract Two human lymphoblastoid cell lines were established by the transformation of human cordโblood lymphocytes with transforming EpsteinโBarr virus (EBV). One cell line (HLBโR1) was established with EBV obtained after the superinfection of Raji cells with HRโ1 EBV and the other (HLBโB1) was
Complexity of EBV homologous DNA in continuous lymphoblastoid cell lines
โ Scribed by Randall Pritchett; Margaret Pedersen; Elliott Kieff
- Book ID
- 119009202
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 407 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0042-6822
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๐ SIMILAR VOLUMES
## Abstract The __in vitro__ and in vivo growth of lymphoblastoid cell lines (LCLs), Burkitt lymphomas (BLs) and PBLโderived immunoblastomas in SCID mice was studied in parallel. Most, but not all, of the LCLs tested were tumorigenic in SCID mice. Longโterm culturing __in vitro__ was not a necessar
The localization of Epstein-Barr virus (EBV) genomes in nuclei of the human lymphoblastoid cell lines Raji, Jijoye, P3HR-1, Daudi and Ramos was investigated by in situ hybridization with biotinylated EBV DNA probes. We found that all sites of hybridization were associated with the chromosomes. Only