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Gel filtration of a complex of DNA polymerase and DNA precursor-synthesizing enzymes from a human lymphoblastoid cell line

โœ Scribed by R.Gitendra Wickremasinghe; John C. Yaxley; A.Victor Hoffbrand


Book ID
119119205
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
433 KB
Volume
740
Category
Article
ISSN
0167-4781

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The effect of L-asparaginase (L-asp) pre-treatment on etoposide-induced DNA strand breakage and cytotoxicity was investigated. In a 1-lymphoblastoid cell line, Molt 4, etoposideinduced DNA strand breaks, DNA-protein cross-links and cytotoxicity were reduced by pre-treatment with L-asp for I 5 hr, bu