Mutated constituents of the DNA replication complex might contribute to the mutational load of the genome during tumor development by impairing DNA synthesis as well as cell cycle-related control of DNA replication. To prove or disprove this hypothesis, we looked for mutations in the cDNA sequences
Activity levels of mouse DNA polymerase α-primase complex (DNA replicase) and DNA polymerase α, free from primase activity in synchronized cells, and a comparison of their catalytic properties
✍ Scribed by Tomoko KOZU; Takeshi SENO; Tatsuo YAGURA
- Book ID
- 115124529
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 984 KB
- Volume
- 157
- Category
- Article
- ISSN
- 1432-1327
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We investigated the association of DNA polymerase and DNA primase activity with the nuclear matrix in HeLa S3 cells diluted with fresh medium after having been cultured without any medium change for 7 days. Flow cytometric analysis demonstrated that just before dilution about 85% of the cells were i
We have investigated whether or not ATP or other nucleoside di-and trisphosphates (including some nonhydrolysable ATP analogues) can stimulate the activity and/or the processivity of DNA polymerase a: associated with the nuclear matrix obtained from HeLa S3 cell nuclei that had been stabilized at 37