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Comparison of two methods for amniotic fluid cholinesterases identification in the qualitative test for prenatal diagnosis of neural tube defects

✍ Scribed by Anna Jeziorowska; Lucjusz Jakubowski; Andrzej Armatys; Bogdan Kałużewski


Book ID
115824622
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
510 KB
Volume
143
Category
Article
ISSN
0009-8981

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Amniotic fluid cholinesterase of valproa
✍ Mohamed M. A. Elmazar; Richard Vogel; Horst Spielmann 📂 Article 📅 1988 🏛 Springer-Verlag 🌐 English ⚖ 321 KB

After a single administration of the antiepileptic drug valproic acid (VPA; i.p.:600 mg/kg) on day 8 of gestation in the mouse embryotoxicity and amniotic fluid (AF) cholinesterase (ChE) were evaluated on day 16 of gestation. VPA treatment induced an increase in embryolethality, neural tube defects