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POLYACRYLAMIDE GEL ELECTROPHORESIS OF AMNIOTIC FLUID CHOLINESTERASES: A GOOD PRENATAL TEST FOR NEURAL TUBE DEFECTS

✍ Scribed by Mary J. Seller; Kathleen J. Cole


Book ID
111152088
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
428 KB
Volume
87
Category
Article
ISSN
1470-0328

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Amniotic fluid cholinesterase of valproa
✍ Mohamed M. A. Elmazar; Richard Vogel; Horst Spielmann πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 321 KB

After a single administration of the antiepileptic drug valproic acid (VPA; i.p.:600 mg/kg) on day 8 of gestation in the mouse embryotoxicity and amniotic fluid (AF) cholinesterase (ChE) were evaluated on day 16 of gestation. VPA treatment induced an increase in embryolethality, neural tube defects