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Value of glial fibrillary acidic protein determination in amniotic fluid for prenatal diagnosis of neural tube defects

✍ Scribed by Nicole Van Regemorter; Jan Gheuens; Mark Noppe; Esther Vamos; Mary J. Seller; Armand Lowenthal


Book ID
115825767
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
443 KB
Volume
165
Category
Article
ISSN
0009-8981

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Amniotic fluid cholinesterase of valproa
✍ Mohamed M. A. Elmazar; Richard Vogel; Horst Spielmann πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 321 KB

After a single administration of the antiepileptic drug valproic acid (VPA; i.p.:600 mg/kg) on day 8 of gestation in the mouse embryotoxicity and amniotic fluid (AF) cholinesterase (ChE) were evaluated on day 16 of gestation. VPA treatment induced an increase in embryolethality, neural tube defects