๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Comparison of the Plasma, Urine and Blister Fluid Pharmacokinetics of Clarithromycin and Azithromycin in Normal Subjects

โœ Scribed by Dr Guy W. Amsden, Charles H. Ballow, Alan Forrest

Book ID
119929174
Publisher
Springer International Publishing AG
Year
1997
Tongue
English
Weight
794 KB
Volume
13
Category
Article
ISSN
1179-1918

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After a single oral dose of (R,S)-ibuprofen (1200 mg) to five healthy volunteers, paired plasma and blister fluid concentrations of drug were determined by a stereospecific HPLC assay. A pharmacokinetic model that incorporated blister fluid as a separate peripheral compartment adequately characteriz