After a single oral dose of (R,S)-ibuprofen (1200 mg) to five healthy volunteers, paired plasma and blister fluid concentrations of drug were determined by a stereospecific HPLC assay. A pharmacokinetic model that incorporated blister fluid as a separate peripheral compartment adequately characteriz
Plasma and skin suction-blister-fluid pharmacokinetics and time course of the effects of oral mizolastine
β Scribed by O. Chosidow; C. Dubruc; P. Danjou; E. Fuseau; E. Espagne; G. Bianchetti; J. P. Thenot; S. Herson; P. Rosenzweig; J. Revuz
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 340 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0031-6970
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