𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human plasma and skin blister fluid levels of griseofulvin following a single oral dose

✍ Scribed by M. Schäfer-Korting; H. C. Korting; E. Mutschler


Publisher
Springer
Year
1985
Tongue
English
Weight
531 KB
Volume
29
Category
Article
ISSN
0031-6970

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Two-stage penetration of a single oral d
✍ A. Nowak; A. Klimowicz 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 411 KB

The time-dependent concentration curves of sulphadimethoxine in plasma and cantharidin-induced skin blister fluid have been evaluated following a single oral dose of 1 g. In contrast to other drugs, sulphadimethoxine exhibited two-stage penetration into the blister fluid, the second peak concentrati

Determination of acitretin in the skin,
✍ Jean-Philippe Laugier; Christian Surber; Hot Bun; Jean-Marie Geiger; Klaus-Peter 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 639 KB

Several HPLC methods for quantification of acitretin and its 13-cis isomer in biological fluids have been described. Only limited data are available on determination of this drug in skin samples. Our objective was to improve the sensitivity and selectivity of existing methods to measure drug in smal

Determination of 8-methoxypsoralen level
✍ H. Ch. Korting; M. Schäfer-Korting; E. Roser-Maass; E. Mutschler 📂 Article 📅 1981 🏛 Springer-Verlag 🌐 English ⚖ 617 KB

An improved fluorodensitometric assay for the determination of 8methoxypsoralen (8-MOP) in plasma is described. Because of its low limit of detection (below 1 rig/spot) this method is suitable to determine the drug in skin suction blister fluid, too. The standard deviation of the procedure is 6.4 %

Application of a modified calorimetric e
✍ Peter A.D. Edwardson; John D. Nichols; Keith Sugden 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 405 KB

A modified enzyme-based colorimetric method has been used to determine plasma paracetamol profiles following single dose (2 x 500 mg) administration of three dosage forms to non-patient volunteers. The assay is linear over the concentration range 0.15-60 micrograms ml-1 with a coefficient of variati