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Comparison of radiation- and chemically-induced dominant lethal mutations in male mice

โœ Scribed by U.H. Ehling


Book ID
116036270
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
585 KB
Volume
11
Category
Article
ISSN
0027-5107

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Induction of dominant lethal mutations i
โœ U. H. Ehling ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal