Comparative pharmacokinetics of coumarin anticoagulants XXXV: Examination of possible pharmacokinetic interaction between (R)-(+)- and (S)-(−)-warfarin in humans
✍ Scribed by Gerhard Levy; Robert A. O'Reilly; Lemuel B. Wingard Jr.
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 210 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
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The anticoagulant warfarin exemplifies a type of drug that exhibits high affinity to pharmacologic target sites of limited capacity, resulting in unusual concentration-dependent distribution and elimination properties. The time course of warfarin concentrations in the serum, liver, kidneys, muscle,
I?)-(+)and (S)-(-)-Warfarin in Humans ~ Keyphrases 0 Warfarin-(R)-(+)-and (S)-(-)-enantiomers, steadystate anticoagulant activity compared Coumarin anticoagulantswarfarin, (R)-(+ )-and (,V)-(-)-enantiomers, steady-state anticoagulant activity compared Pharmacokinetics-(R)-(+)and (S)-(-)-warfarin, st