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Comparative pharmacokinetics of coumarin anticoagulants XLV: Pharmacokinetic and pharmacodynamic studies of acute interaction between warfarin and phenylbutazone in rats

✍ Scribed by Avraham Yacobi; Chii-Ming Lai; Gerhard Levy

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 851 KB
Volume: 69
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600690105

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d e n quantitation of small sulfamethazine peaks impractical. The chloroform wash of the basic aqueous mixture seems to affect this component m a t . Overwashing at this point, however, causes a loss of sulfamethazine. Homogenizing or grinding the tissue prior to extraction tends to improve recover