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Comparative behavioral characterization of the neuroactive steroids 3α-OH,5α-pregnan-20-one and 3α-OH,5β-pregnan-20-one in rodents

✍ Scribed by Scott Wieland; Nancy C. Lan; James D. Belluzzi; Larry Stein


Publisher
Springer
Year
1995
Tongue
English
Weight
893 KB
Volume
118
Category
Article
ISSN
0033-3158

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📜 SIMILAR VOLUMES


Synthesis of 5α-pregnane-3β,20α-diol and
✍ T. A. Baillie; J. E. Herz; J. Sjövall 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 French ⚖ 241 KB 👁 1 views

## Abstract A convenient synthesis of 5α‐[20β‐^2^H]pregnane‐3α,20α‐diol and 5α‐[20β‐^2^H]pregnane‐3β,20α‐diol from 3β‐hydroxy‐5α‐pregn‐16‐en‐20‐one is described. The reaction products are characterized by combined gas chromatography‐mass spectrometry.

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THE total synthesis of several steroids (1.2) has previously been reported from this laboratory. In this communication a straightforward total synthesis of rec. 5a-preQnan-3~-ol-20-one (XIIIa) is reported. '3 All melting points were measured on Kofler block and corrected. '