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The neurosteroid 3α-hydroxy-5α-pregnan-20-one affects dopamine-mediated behavior in rodents

✍ Scribed by Rahul T. Khisti; Laxmikant S. Deshpande; Chandrabhan T. Chopde


Publisher
Springer
Year
2002
Tongue
English
Weight
155 KB
Volume
161
Category
Article
ISSN
0033-3158

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## Abstract A procedure for the biosynthetic preparation of 3α‐hydroxy‐5α‐[1,2,6,7‐^3^H]‐pregnan‐20‐one (^3^H‐HPO) with high specific activity convenient for binding studies was developed. ^3^H‐HPO was synthesized from [1,2,6,7‐^3^H]progesterone using a microsomal preparation from rat liver and NAD