✦ LIBER ✦

Compact Tunable Cr:LiSAF Laser for Infrared Matrix-assisted Laser Desorption/Ionization

✍ Scribed by Mehrnoosh Sadeghi; Zohra Olumee; Xiaodong Tang; Akos Vertes; Zhi-Xing Jang; Angus J. Henderson; Hyo Sang Lee; Coorg R. Prasad

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 105 KB
Volume: 11
Category: Article
ISSN: 0951-4198
DOI: 10.1002/(sici)1097-0231(19970228)11:4<393::aid-rcm868>3.0.co;2-s

No coin nor oath required. For personal study only.

✦ Synopsis

A tunable Cr:LiSAF laser-pumped optical parametric oscillator was used for mid-infrared matrix-assisted laser desorption/ionization (MALDI) mass spectrometry experiments. The mass spectra of substance P, bovine insulin and pd(T) 10 in the 2.88-2.96 µm range showed excellent single shot signal quality (signal-to-noise-ratio, resolution) but poor shot-to-shot reproducibility. The reproducibility is expected to improve with more stable laser design. No correlation was found between the absorption sepectrum of the matrix and the MALDI response.

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