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Common variation in the LRRK2 gene is a risk factor for Parkinson's disease

✍ Scribed by Mata, Ignacio F.; Checkoway, Harvey; Hutter, Carolyn M.; Samii, Ali; Roberts, John W.; Kim, Hojoong M.; Agarwal, Pinky; Alvarez, Victoria; Ribacoba, Renee; Pastor, Pau; Lorenzo-Betancor, Oswaldo; Infante, Jon; Sierra, María; Gómez-Garre, Pilar; Mir, Pablo; Ritz, Beate; Rhodes, Shannon L.; Colcher, Amy; Van Deerlin, Vivianna; Chung, Kathryn A.; Quinn, Joseph F.; Yearout, Dora; Martinez, Erica; Farin, Federico M.; Wan, Jia Y.; Edwards, Karen L.; Zabetian, Cyrus P.


Book ID
118764325
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
186 KB
Volume
27
Category
Article
ISSN
0885-3185

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## Abstract Common genetic variants that increase the risk for Parkinson's disease may differentiate patient subgroups and influence future individualized therapeutic strategies. Herein we show evidence for __leucine‐rich repeat kinase 2 (LRRK2)__ c.4883G>C (R1628P) as a risk factor in ethnic Chine