Combining Association Tests across Multiple Genetic Markers in Case-Control Studies
β Scribed by Zhou, Huanyu; Wei, Lee-Jen; Xu, Xiping; Xu, Xin
- Book ID
- 120405318
- Publisher
- S. Karger AG
- Year
- 2008
- Tongue
- English
- Weight
- 243 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0001-5652
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract For a dense set of genetic markers such as single nucleotide polymorphisms (SNPs) on high linkage disequilibrium within a small candidate region, a haplotypeβbased approach for testing association between a disease phenotype and the set of markers is attractive in reducing the data comp
## Abstract Multivariate phenotypes are frequently encountered in genomeβwide association studies (GWAS). Such phenotypes contain more information than univariate phenotypes, but how to best exploit the information to increase the chance of detecting genetic variant of pleiotropic effect is not alw