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Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia

✍ Scribed by Schroers, R; Griesinger, F; Trümper, L; Haase, D; Kulle, B; Klein-Hitpass, L; Sellmann, L; Dührsen, U; Dürig, J


Book ID
110056229
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
291 KB
Volume
19
Category
Article
ISSN
0887-6924

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## Abstract ## Background: Zeta‐chain associated protein of 70kDa (ZAP‐70) is the most promising surrogate marker for the immunoglobulin heavy chain variable region (IgV~H~) mutation status in B‐cell chronic lymphocytic leukemia (B‐CLL). Crespo et al. proposed the detection of ZAP‐70 by flow cytom