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Collagen-apatite nanocomposite membranes for guided bone regeneration

✍ Scribed by Ju-Ha Song; Hyoun-Ee Kim; Hae-Won Kim

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
658 KB
Volume
83B
Category
Article
ISSN
1552-4973

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✦ Synopsis

Abstract

Collagen‐apatite nanocomposite is regarded as a potential biomaterial because of its composition and structure, which are similar to those of human hard tissues. However, there have been few investigations of its mechanical and biological benefits in direct comparison with a collagen equivalent. Herein, we successfully produced a biomedical membrane made of a nanocomposite, and systemically evaluated the mechanical, chemical, and biological properties of the nanocomposite in comparison with those of pure collagen. The results showed that significant improvements were achieved by the nanocomposite approach, particularly in terms of the mechanical strength and chemical stability. The present findings point to the potential usefulness of the collagen‐apatite nanocomposite membrane in the field of guided bone regeneration (GBR). © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2007

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