Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan
β Scribed by Hiroto Narimatsu; Masaki Iino; Takuji Ichihashi; Toshiya Yokozawa; Masaya Hayakawa; Hitoshi Kiyoi; Takaaki Takeo; Akiyo Sawamoto; Hiroatsu Iida; Motohiro Tsuzuki; Masamitsu Yanada; Tomoki Naoe; Ritsuro Suzuki; Isamu Sugiura
- Book ID
- 107618559
- Publisher
- Carden Jennings Publishing
- Year
- 2008
- Tongue
- English
- Weight
- 205 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0925-5710
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t(8;21) is one of the common chromosomal translocations in acute myelogenous leukemia (AML). Using a recently developed real-time quantitative polymerase chain reaction (PCR) system, we analyzed the minimal residual disease (MRD) in bone marrow samples from seven AML patients with t(8;21) at differe
## Abstract ## Background Minimal residual disease (MRD) detected during remission might predict outcome in children with acute lymphoblastic leukemia. No populationβbased studies have been carried out. We studied all children with ALL presenting over 5 years within a defined population to determi