Clinical significance of minimal residual disease in adult acute lymphoblastic leukemia
β Scribed by Misato Kikuchi; Junji Tanaka; Takeshi Kondo; Satoshi Hashino; Masaharu Kasai; Mitsutoshi Kurosawa; Hiroshi Iwasaki; Masanobu Morioka; Tsugumichi Kawamura; Nobuo Masauzi; Takashi Fukuhara; Yasutaka Kakinoki; Hajime Kobayashi; Satoshi Noto; Masahiro Asaka; Masahiro Imamura
- Book ID
- 107619120
- Publisher
- Carden Jennings Publishing
- Year
- 2010
- Tongue
- English
- Weight
- 276 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0925-5710
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## Abstract ## Background Minimal residual disease (MRD) detected during remission might predict outcome in children with acute lymphoblastic leukemia. No populationβbased studies have been carried out. We studied all children with ALL presenting over 5 years within a defined population to determi
## Abstract Two highly sensitive methods, multiparameter flow cytometry (MFC) and realβtime quantitative PCR (RQβPCR), are increasingly used to monitor minimal residual disease (MRD) and to guide riskβadapted management in acute myeloid leukemia (AML). An independent prognostic impact has been demo