Detection of minimal residual disease in acute myeloid leukemia
β Scribed by Maria R. Baer
- Book ID
- 107546145
- Publisher
- Current Science Inc.
- Year
- 2002
- Tongue
- English
- Weight
- 236 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1523-3790
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background: Multiparameter flow cytometry (MFC) has been shown to be a useful approach for detection of minimal residual disease (MRD). The aim of the study was to determine the optimal threshold that can separate patients into two groups in terms of leukemic residual cells and rela
## Abstract Two highly sensitive methods, multiparameter flow cytometry (MFC) and realβtime quantitative PCR (RQβPCR), are increasingly used to monitor minimal residual disease (MRD) and to guide riskβadapted management in acute myeloid leukemia (AML). An independent prognostic impact has been demo
Patients with acute leukemia in clinical remission may still have up to 10 10 residual malignant cells (the upper limit of detection by standard morphologic techniques). Sensitive techniques to detect minimal residual disease (MRD) may allow better estimates of the leukemia burden and help the selec