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Clinical differences between children and adults with pulmonary hypertension and sickle cell disease

✍ Scribed by R. Ward Hagar; Jennifer G. Michlitsch; Jennifer Gardner; Elliott P. Vichinsky; Claudia R. Morris


Book ID
108675445
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
146 KB
Volume
0
Category
Article
ISSN
0007-1048

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In patients with sickle cell disease, anemia is a recognized risk factor for stroke, death, and the development of pulmonary hypertension. We have proposed that hemolytic anemia results in endothelial dysfunction and vascular instability and can ultimately lead to a proliferative vasculopathy leadin