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Chromosome Translocations in Breast Cancer with Breakpoints at 8p12

✍ Scribed by Celine Courtay-Cahen; Joanna S. Morris; Paul A.W. Edwards


Book ID
115615094
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
223 KB
Volume
66
Category
Article
ISSN
0888-7543

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A subgroup of pleomorphic adenomas of the salivary glands is characterized by translocations involving chromosome 8, with consistent breakpoints at 8q 12. As part of a positional cloning effort to isolate the gene(s) affected by these translocations we now report the mapping of the 8q I 2 breakpoint