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A Translocation Breakpoint at Chromosome Band 12q13 Associated with B-Cell Chronic Lymphocytic Leukemia

✍ Scribed by A.Dean Stock; Thomas R Dennis


Book ID
114136887
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
540 KB
Volume
111
Category
Article
ISSN
0165-4608

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We performed cytogenetic analyses of peripheral blood lymphocytes from 82 Midwestern B-cell chronic lymphocytic leukemia (B-CLL) patients. The cells were cultured with mitogens for 3 4 days. At least I 5 metaphase cells were analyzed in 79 (96%) cases. Fifty (63%) of the 79 patients had clonal chrom