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Chromosome 8 pentasomy with partial tandem duplication of 11q23 in a case of de novo acute myeloid leukemia

✍ Scribed by So Youn Shin; Sun Hoe Koo; Kye Chul Kwon; Jong Woo Park; Jeong Hoon Song; Young Hyun Ko; Deog Yeon Jo

Book ID
113513581
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
266 KB
Volume
194
Category
Article
ISSN
0165-4608

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## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte