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Pentasomy 21 with two isochromosomes 21 in a case of acute myeloid leukemia without maturation

✍ Scribed by Marta Salido; Francesc Solé; Blanca Espinet; Cristalina Fernández; Lourdes Zamora; Soledad Woessner; Lourdes Florensa


Book ID
114135193
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
271 KB
Volume
132
Category
Article
ISSN
0165-4608

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An 8 2 I translocation is a common chromosome abnormality associated with acute myeloblastic leukemia with maturation (M2 of French-American-British (FAB) classification). W e have isolated chromosome 2 I Nod linking clones; pulsed field gel electrophoresis analysis with one clone (LL263) detected a