## Abstract In this study we compare the cellular control of recombinant human IgG~4~ monoclonal antibody (Mab) synthesis in different CHO cell lines. Based on comprehensive empirical analyses of mRNA and polypeptide synthetic intermediates we constructed cell lineโspecific mathematical models of r
โฆ LIBER โฆ
CHO cell line specific prediction and control of recombinant monoclonal antibody N -glycosylation
โ Scribed by Grainger, Rhian K.; James, David C.
- Book ID
- 120413919
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 446 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0006-3592
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Cell line-specific control of recombinan
โ
Peter M. O'Callaghan; Jane McLeod; Leon P. Pybus; Clare S. Lovelady; Stephen J.
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 440 KB
๐ 1 views
Metabolic control of recombinant monoclo
โ
Anna E. Hills; Ashvin Patel; Paul Boyd; David C. James
๐
Article
๐
2001
๐
John Wiley and Sons
๐
English
โ 246 KB
๐ 1 views
A mechanistic understanding of productio
โ
Minsoo Kim; Peter M. O'Callaghan; Kurt A. Droms; David C. James
๐
Article
๐
2011
๐
John Wiley and Sons
๐
English
โ 321 KB
๐ 1 views
Control of Culture Environment for Impro
โ
Douglas J. Galbraith; Andrew S. Tait; Andrew J. Racher; John R. Birch; David C.
๐
Article
๐
2006
๐
American Institute of Chemical Engineers
๐
English
โ 168 KB
Identification of cell culture condition
โ
Martin Gawlitzek; Michael Estacio; Tobias Fรผrch; Robert Kiss
๐
Article
๐
2009
๐
John Wiley and Sons
๐
English
โ 629 KB
## Abstract The effect of different cell culture conditions on __N__โglycosylation siteโoccupancy has been elucidated for two different recombinant glycoproteins expressed in Chinese hamster ovary (CHO) cells, recombinant human tissue plasminogen activator (tโPA) and a recombinant enzyme (glycoprot
Influence of culture conditions on the N
โ
Gleysin Cabrera; Josรฉ A. Cremata; Rodolfo Valdรฉs; Rossana Garcรญa; Yanelys Gonzรกl
๐
Article
๐
2005
๐
Portland Press
๐
English
โ 165 KB