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Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans

✍ Scribed by AC Gebhardt; D Lucas; J Menez; HK Seitz

Book ID
118686703
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
211 KB
Volume
26
Category
Article
ISSN
0270-9139

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πŸ“œ SIMILAR VOLUMES

Chlormethiazole inhibition of cytochrome
Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans
✍ A C Gebhardt; D Lucas; J Menez; H K Seitz πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 213 KB

Chlormethiazole is a sedative and anticonvulsive drug used in the treatment of alcohol withdrawal. Because it had been reported that chlormethiazole inhibits the alcohol-inducible cytochrome P450 2E1 in rat liver, we investigated the in vivo and in vitro effect of this drug on cytochrome P450 2E1 in