Chlormethiazole inhibition of cytochrome
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A C Gebhardt; D Lucas; J Menez; H K Seitz
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Article
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1997
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John Wiley and Sons
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English
⚖ 213 KB
Chlormethiazole is a sedative and anticonvulsive drug used in the treatment of alcohol withdrawal. Because it had been reported that chlormethiazole inhibits the alcohol-inducible cytochrome P450 2E1 in rat liver, we investigated the in vivo and in vitro effect of this drug on cytochrome P450 2E1 in