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Chiral separation of basic drugs using cyclodextrins as chiral pseudo-stationary phases in capillary electrophoresis

✍ Scribed by M. Heuermann; G. Blaschke

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
607 KB
Volume
648
Category
Article
ISSN
1873-3778

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πŸ“œ SIMILAR VOLUMES

Separation of basic drugs by capillary e
Separation of basic drugs by capillary electrophoresis using selectively modified cyclodextrins as chiral selectors
✍ Gerald Weseloh; Holger Bartsch; Wilfried A. KΓΆnig πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 474 KB

## Abstract The influence of seven differently methylated β‐cyclodextrin derivatives and of pure β‐cyclodextrin (β‐CD) on the enantiomeric resolution by capillary electrophoresis of six basic chiral pharmaceuticals is investigated. The methyl substitution pattern affects enantioselectivity much mor

Evaluation of the use of cyclodextrins i
Evaluation of the use of cyclodextrins in chiral separation of basic drug substances by capillary electrophoresis
✍ Dr. Inga BjΓΈrnsdottir; Steen HonorΓ© Hansen πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 442 KB πŸ‘ 1 views

The influence of the choice of type and/or concentration of cyclodextrin, other additives, the temperature surrounding the capillary, and buffer pH on the separation of some chiral basic drug substances in capillary zone electrophoresis has been evaluated. It was found that pH of the buffer and type