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Chemopreventive properties of nimesulide, a selective cyclooxygenase-2 inhibitor, against phip-induced mammary carcinogenesis in rats

✍ Scribed by Toshihiko Kawamori; Seiichi Nakatsugi; Toshihisa Ohta; Takashi Sugimura; Keiji Wakabayashi

Book ID: 114101079
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 71 KB
Volume: 59
Category: Article
ISSN: 0090-6980
DOI: 10.1016/s0090-6980(99)90247-2

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## Abstract The modification effects of nimesulide, a cyclooxygenase (COX)‐2 inhibitor, administration during the postinitiation phase of pancreatic carcinogenesis were investigated in hamsters treated with __N__‐nitrosobis(2‐oxopropyl)amine (BOP). Male Syrian hamsters were given 4 weekly s.c. inje