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Effect of the selective cyclooxygenase-2 inhibitor nimesulide on kainate-induced seizures in the rat brain

✍ Scribed by Tina Kunz; Ernst H. Oliw

Book ID
114101287
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
74 KB
Volume
59
Category
Article
ISSN
0090-6980

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πŸ“œ SIMILAR VOLUMES

Effects of nimesulide on kainate-induced
Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates
✍ Eduardo Candelario-Jalil; Olga Sonia LeΓ³n πŸ“‚ Article πŸ“… 2003 πŸ› BioMed Central 🌐 English βš– 646 KB

## Background: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. ## Results: Exposur