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Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta

✍ Scribed by Claire Connolly; P.A McCormick; J.R Docherty

Book ID
114016353
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
108 KB
Volume
352
Category
Article
ISSN
0014-2999

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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in