2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), a compound found in cooked meat, is a mammary gland carcinogen in female Sprague-Dawley rats. PhIP-induced rat mammary gland carcinomas were examined for mutations in several genes (exons) known to regulate cell growth and apoptosis, including
Chemoprevention by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced Mammary Gland Carcinogenesis in Rats
β Scribed by Nakatsugi, Seiichi ;Ohta, Toshihisa ;Kawamori, Toshihiko ;Mutoh, Michihiro ;Tanigawa, Tetsuya ;Watanabe, Kouji ;Sugie, Shigeyuki ;Sugimura, Takashi ;Wakabayashi, Keiji
- Book ID
- 108581959
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2000
- Tongue
- English
- Weight
- 155 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0910-5050
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