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Chemo-biocatalytic regioselective one-pot synthesis of different deprotected monosaccharides

✍ Scribed by Marco Filice; Teodora Bavaro; Roberto Fernandez-Lafuente; Massimo Pregnolato; Jose M. Guisan; Jose M. Palomo; Marco Terreni

Book ID: 104010174
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 712 KB
Volume: 140
Category: Article
ISSN: 0920-5861
DOI: 10.1016/j.cattod.2008.07.016

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## Abstract An efficient, one‐pot, multicomponent reaction of aldehydes **1**, __p__‐methoxyaniline (**2a**), and 2‐vinylindoles **3** was developed. This approach provides a practical approach to synthetically and biologically significant tetrahydro‐γ‐carboline and tetrahydroquinoline derivatives