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One-pot chemo-biocatalytic synthesis of R-1-phenylethyl acetate from acetophenone hydrogenation over Pd/Al2O3 catalyst

✍ Scribed by Päivi Mäki-Arvela; Serap Sahin; Narendra Kumar; Teemu Heikkilä; Vesa-Pekka Lehto; Tapio Salmi; Dmitry Yu. Murzin

Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 476 KB
Volume: 350
Category: Article
ISSN: 0926-860X
DOI: 10.1016/j.apcata.2008.07.039

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## Abstract **BACKGROUND:** A systematic investigation of mutual interference between a hydrogenation catalyst, Pd/Al~2~O~3~, and an immobilized lipase in a one‐pot synthesis of __R__‐1‐phenyl ethyl acetate at 70 °C has been undertaken. This paper reports the kinetic modeling of lipase‐mediated che