ChemInform Abstract: Convenient Synthesis of Tetrahydro-γ-carbolines and Tetrahydroquinolines Through a Chemo- and Regioselectivity Switch by a Broensted Acid Catalyzed, One-Pot, Multicomponent Reaction.

Convenient Synthesis of Tetrahydro-γ-car

Convenient Synthesis of Tetrahydro-γ-carbolines and Tetrahydroquinolines through a Chemo- and Regioselectivity Switch by a Brønsted Acid Catalyzed, One-Pot, Multicomponent Reaction

✍ Hong-Gang Cheng; Cai-Bao Chen; Fen Tan; Ning-Jie Chang; Jia-Rong Chen; Wen-Jing 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB

## Abstract An efficient, one‐pot, multicomponent reaction of aldehydes **1**, __p__‐methoxyaniline (**2a**), and 2‐vinylindoles **3** was developed. This approach provides a practical approach to synthetically and biologically significant tetrahydro‐γ‐carboline and tetrahydroquinoline derivatives