๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Chemistry of FK-506: Benzilic acid rearrangement of the tricarbonyl system

โœ Scribed by D. Askin; R.A. Reamer; T.K. Jones; R.P. Volante; I. Shinkai

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
237 KB
Volume
30
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

Treatment of FK-506 with aqueous hydroxide results in a benzilic acid rearrangement of the C.8-c.10 tricarbonyl portion of the molecule. A corrected structure for a previously reported degradation product as well as oxidative decarboxylation of rearranged IX-506 is presented.

๐Ÿ“œ SIMILAR VOLUMES

Thermal rearrangement of the immunosuppr
Thermal rearrangement of the immunosuppressant FK-506
โœ H. Ok; B.H. Arison; R.G. Ball; T.R. Beattie; M.H. Fisher; M.J. Wyvratt ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 218 KB

Treatment of FK-506 in xylene at rcflux results in a 13.31 sigmatropic