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ChemInform Abstract: Total Synthesis of Pinnatoxin A.

✍ Scribed by J. A. MCCAULEY; K. NAGASAWA; P. A. LANDER; S. G. MISCHKE; M. A. SEMONES; Y. KISHI


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


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Total Synthesis of (-)-Epothilone A. -A key step in the synthesis of the title antitumor natural product is the highly stereoselective aldol reaction of the optically active building blocks (I) and (II). Esterification of the product (IV) with the subunit (V) leads to the stereochemically homogeneou