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ChemInform Abstract: Total Synthesis of (+)-Brefeldin A (I).

✍ Scribed by Yikang Wu; Jian Gao


Publisher
John Wiley and Sons
Year
2008
Weight
16 KB
Volume
39
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


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A Formal Synthesis of (+)-Brefeldin A. -An advanced synthetic intermediate for (+)-brefeldin A (IX) is efficiently synthesized from Weinreb amide (I). The procedure involves the highly stereoselective construction of the hydroxycyclopentane moiety via an oxabicycloheptanone unit. -(SUH,