𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: The De Novo Design and Synthesis of Cyclic Urea Inhibitors of Factor Xa: Optimization of the S4 Ligand.

✍ Scribed by Robert A. Galemmo Jr.; et al. et al.


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
31
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


πŸ“œ SIMILAR VOLUMES


ChemInform Abstract: The DE Novo Design
✍ R. A. JUN. GALEMMO; T. P. MADUSKUIE; C. DOMINGUEZ; K. A. ROSSI; R. M. KNABB; R. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

The DE Novo Design and Synthesis of Cyclic Urea Inhibitors of Factor Xa: Initial SAR Studies. -A series of cyclic ureas is prepared and tested as inhibitors of the blood coagulation protein factor Xa. Molecular modelling calculations are performed to study the docking of the compounds to the factor

ChemInform Abstract: The Synthesis and E
✍ M. PATEL; L. T. BACHELER; M. M. RAYNER; B. C. CORDOVA; R. M. KLABE; S. ERICKSON- πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,