## Abstract Reaction of 2‐aminopyrazine 1 with isothiocyanate, isocyanate or dithioketal reagent furnished pteridines **3,4** in good yield. Thioxo compound **3a** was chlorinated, methylated and subsequently displaced by amines. A simple one‐step synthesis of heterocondensed pteridines **8–13** by
ChemInform Abstract: Synthesis of New Heterocondensed Pteridines.
✍ Scribed by A. Z. M. Shaifullah Chowdhury; Yasuyuki Shibata; Masatoshi Morita; Kunimitsu Kaya; Kazuhisa Hiratani
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract A new synthesis of pteridines possessing a (substituted) (__Z__)‐3‐hydroxyprop‐1‐enyl group at C(6) is based on the acylation of 4‐amino‐5‐nitrosopyrimidines with dienoic acid chlorides, followed by a high‐yielding intramolecular hetero‐__Diels–Alder__ cycloaddition and cleavage of the