Microwave-Assisted Preparation of Isatins and Synthesis of (ยฑ)-Convolutamydine-A. -A microwave assisted synthesis of isostatin derivatives (IV) (8 examples) is reported. Using this new strategy, the alkaloid (ยฑ)-convolutamydine-A (VI), a potential reagent against leukemia, is synthesized. -(JNANESH
ChemInform Abstract: Synthesis of Convolutamydine A from Isatin.
โ Scribed by G. K. Jnaneshwar; V. H. Deshpande
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Synthesis of the Marine Dibromooxoindoline Convolutamydine C. -The first synthesis of convolutamydine C (XIII) is described. Key steps are the Rh(II) perfluorobutyramide catalyzed cyclization of diazoamide (V) and the subsequent high yielding one-pot hydrolysis-decarboxylation-oxidation of oxoindoli
A Modified Sandmeyer Methodology and the Synthesis of (ยฑ)-Convolutamydine A. -A modified Sandmeyer methodology (lower temperature and addition of ethanol) is found to be useful for the high yield synthesis of ฮฑ-isonitrosoacetanilides (III). Derivative (IIIc) is readily converted to (ยฑ)-convolutamyd