𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis of 9-Fluorenylmethyl Esters Using 9-Fluorenylmethyl Chloroformate.

✍ Scribed by S. A. M. Merette; A. P. Burd; J. J. Deadman

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis of 9-Fluorenylmethyl Esters Using 9-Fluorenylmethyl Chloroformate.

-In the presence of (iPr) 2 NEt as base and catalytic amounts of DMAP, N-Boc protected amino acids are directly converted to the related esters by 9-fluorenylmethyl chloroformate without racemization. The products are suitable substrates in solid-phase syntheses.

-(MERETTE,

πŸ“œ SIMILAR VOLUMES

9-Fluorenylmethoxycarbonylpyroglutamate,
9-Fluorenylmethoxycarbonylpyroglutamate, a side-product of derivatization of glutamate with 9-fluorenylmethyl chloroformate: A warning
✍ Hans-JΓΆrg Keller; Kim Quang Do; Markus Zollinger; Kaspar H. Winterhalter; Michel πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 English βš– 270 KB

9-Fluorenylmethyl chloroformate derivatization is widely used for determinations of amino acids in biological material. The derivatization of glutamate leads to the formation of 9-fluorenylmethoxycarbonylpyroglutamate as a side-product, which is thus a methodological artifact.

LC method for the analysis of kanamycin
LC method for the analysis of kanamycin residue in swine tissues using derivatization with 9-fluorenylmethyl chloroformate
✍ Yiqiang Chen; Qian Chen; Shusheng Tang; Xilong Xiao πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 198 KB

## Abstract A sensitive and robust HPLC method was developed for the determination of kanamycin (Kan) in swine tissues. Kan was extracted from tissue with 10% TCA (w/v) solution and cleaned up with MCX SPE column. The purified extract was derivatized with 9‐fluorenylmethyl chloroformate, and then s

Enantiomeric separation by capillary ele
Enantiomeric separation by capillary electrophoresis of di- and tri-peptides derivatized with 9-fluorenylmethyl chloroformate using vancomycin as chiral selector
✍ Hong Wan; Lars G. Blomberg πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 566 KB

Enantiomeric separations of chiral di-and tri-peptides derivatized with 9-fluorenylmethyl chloroformate were carried out by capillary electrophoresis using vancomycin as a chiral selector. The mobilities of vancomycin were determined in phosphate and HEPES buffer by means of a factorial design. The