✦ LIBER ✦

9-Fluorenylmethoxycarbonylpyroglutamate, a side-product of derivatization of glutamate with 9-fluorenylmethyl chloroformate: A warning

✍ Scribed by Hans-Jörg Keller; Kim Quang Do; Markus Zollinger; Kaspar H. Winterhalter; Michel Cuénod

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 270 KB
Volume: 166
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(87)90595-1

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✦ Synopsis

9-Fluorenylmethyl chloroformate derivatization is widely used for determinations of amino acids in biological material. The derivatization of glutamate leads to the formation of 9-fluorenylmethoxycarbonylpyroglutamate as a side-product, which is thus a methodological artifact.