Other bioactive products U 1300 Synthesis of Racemic Tricyclic 1,2,4-Trioxanes that Are Isomeric to Simplified Analogues of Naturally Occurring Artemisinin. -Key step is the cyclization of a ketone-tethered enol ether to give the novel trioxane framework (II)/(III), simplified analogue of an artemis
ChemInform Abstract: Synthesis of 4-Trifluoromethyl-1,2,4-trioxanes, Simplified Analogues of Artemisinin.
β Scribed by O. PROVOT; H. MOSKOWITZ; J. MAYRARGUE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Alcohol Analogues of the Antimalarial Artemisinin. -A series of the title compounds such as (VIII)-(XI) is synthesized and used in the preparation of derivatives such as (XIII). These products are potent antimalarials with up to 140% of the efficacy of the natural artemisinin. -(CUMMING,
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v