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ChemInform Abstract: Synthesis of 1-O-5-Substituted-deoxy-β-D-ribofuranosides with ( CH3)2As and (CH3)2As=O as Substituents at the 5-Position and a Methyl or 2′,3′-Dihydroxypropyl Group as the Aglycone in the 1-Position.

✍ Scribed by J. LIU; D. H. O'BRIEN; K. J. IRGOLIC

Book ID
112032801
Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
27
Category
Article
ISSN
0931-7597

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✍ Jinggao Liu; Daniel H. O'Brien; Kurt J. Irgolic 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 896 KB

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Eight arsenic-containing ribosides were prepared from dimethyl( 1 -0-methyl1 -5-deoxy-2,3-0-isopropylidene-P-D-ribofuranos-5-yl)arsine and (2's)- Reactions of the arsines with sulfur produced the compounds with a (CH,),As=S group as substituent in the 5-position. Treatment of these dimethyl(ribosy1

ChemInform Abstract: Structure—Activity
ChemInform Abstract: Structure—Activity Relationships of (4-Acylpyrrol-2-yl)alkanoic Acids as Inhibitors of the Cytosolic Phospholipase A2: Variation of the Substituents in Positions 1, 3, and 5.
✍ M. LEHR 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Structure-Activity Relationships of (4-Acylpyrrol-2-yl)alkanoic Acids as Inhibitors of the Cytosolic Phospholipase A 2 : Variation of the Substituents in Positions 1, 3, and5. -Investigation of the structureactivity relationship of lead compounds (I) by variation of the substituents in position 1, 3